ZFIN Image: Misselbeck et al., 2019, Fig. 3

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Fig. 3

Network construction and disease module identification. a Tissue-specific networks were constructed by integrating transcriptional regulatory networks consisting of interactions between transcription factors and genes (blue nodes) and PPI networks including interactions among proteins (turquoise nodes). For each tissue, the integrated network was built starting from the high-evidence associations from the regulatory network and extended with high-score interactions from the PPI network. b Venn diagram of shared MetSyn genes among the three tissue-specific networks. See also Supplementary Data 4

Acknowledgments

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