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Fig. 3
Pax3-GFP responds to Wnt signaling. (A, C, E) ISH for endogenous Pax3 in wild type embryos at the indicated stages. (B, D, F) ISH for GFP in Pax3-GFP transient transgenic embryos at the indicated stages. Embryos were non-injected (Control) or injected with an inducible form of β-catenin (β-Cat-GR) and treated with DXM (in DMSO) to induce β-catenin, or DMSO alone. (G) Quantification of the percentage of embryos that showed expansion in Pax3/GFP expression. Note that activation of β-catenin leads to an equivalent increase of Pax3 and GFP expression. *** P<0.001.
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Reprinted from Developmental Biology, 444 Suppl 1, Alkobtawi, M., Ray, H., Barriga, E.H., Moreno, M., Kerney, R., Monsoro-Burq, A.H., Saint-Jeannet, J.P., Mayor, R., Characterization of Pax3 and Sox10 transgenic Xenopus laevis embryos as tools to study neural crest development, S202-S208, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.