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Figure Caption
Fig. S7 mTORC1 activation in dxavu463 at 6 dpf. (A) Immunoblot blots for phospho-S6Ser235/236 and phosphor-4E-BP1Thr37/46 in control sibling and dxa mutant zebrafish at 6 dpf. (B) Relative ratio of phospho-S6 amount in control and dxa mutants, p = 0.0003. (C) Relative ratio of phosphor-4E-BP1 amount in control and dxa mutants. P = 0.035, n = 5 samples per genotype, each samples contained 2 larvae. p = 0.0246. (D) Phospho-S6 (left panel) and phospho-4E-BP1 staining (right panel) in the liver of WT (top) and type II dxa (bottom) zebrafish at 6 dpf. Scale bar = 100 μm.
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