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Fig. 3 globin expression by in situ hybridization through 5 dpf. Expression patterns of the α- (A) and β-globin (B) genes. For detected genes, expression is seen in bilateral stripes at the 16ss, in the ICM at the 25ss and 24 hpf stage. With the onset of circulation at 24 hpf, globin positive cells can be seen throughout the vasculature with probes for expressed globin genes, particularly in the vascular plexus of the caudal hematopoietic tissue.

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Reprinted from Developmental Biology, 366(2), Ganis, J.J., Hsia, N., Trompouki, E., de Jong, J.L., Dibiase, A., Lambert, J.S., Jia, Z., Sabo, P.J., Weaver, M., Sandstrom, R., Stamatoyannopoulos, J.A., Zhou, Y., and Zon, L.I., Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR, 185-194, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.