ZFIN ID: ZDB-IMAGE-120329-35
Figures for Zhu et al., 2012

Genes:

Figure Caption/Comments:

Fig. 6

MYCN Causes Hu+ Cell Hyperplasia in the Interrenal Gland (A) Sagittal sections through the interrenal gland in DβH (top panels), MYCN (middle panels), and MYCN;ALK (lower panels) transgenic fish at 5wpf (dorsal up, anterior left). EGFP, green; Hu, magenta; TH, red. Representative sections through the interrenal gland in DβH fish contain three to five GFP+/Hu+/TH+ sympathetic neuroblasts (arrows) and many GFP+/Hu-/TH+ chromaffin cells (arrowheads). Hu+ cell numbers increase in MYCN and MYCN;ALK fish (brackets), and can be GFP+ and TH+. Dotted lines indicate the head kidney (HK) boundary. Scale bar represents 20 μm. (B) Numbers of Hu+ interrenal gland cells in DβH, ALK, MYCN, and MYCN;ALK transgenic fish at 3, 5, and 7 weeks. Means of Hu+ cell numbers were compared by the two-tailed Wilcoxon signed-rank test. See also Figure S6.

Figure Data:
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.