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Fig. 5
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Fig. 5
Stages of hematopoiesis in syr.
Early hematopoietic markers are expressed normally in syr at 17–19 hpf (A–D) (note that Figs. 4A and 5C are the same; Fig. 4A/5C is included here for completeness). Definitive hematopoiesis is initiated in syr indicated by runx1 expression at 28 hpf (E–F). Caudal hematopoietic tissue fails to develop in syr indicated by lack of scl1 expression at 3 dpf (G–H). Med12 is expressed in WT and syr with insets showing staining in the hematopoietic ICM region (I–J); dorsal view of staining (K–L). Unless otherwise stated, WISH embryos are representative of e10, and d46, examples.
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