Gene

rxraa

ID
ZDB-GENE-070314-2
Name
retinoid X receptor, alpha a
Symbol
rxraa Nomenclature History
Previous Names
  • NR2B1-B (1)
  • RXRalpha-B (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have nuclear receptor activity and retinoic acid-responsive element binding activity. Predicted to be involved in several processes, including regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to localize to RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including nervous system; neural crest; optic vesicle; segmental plate; and tail bud. Orthologous to human RXRA (retinoid X receptor alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rxraa Human Ortholog
No data available
Associated With rxraa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Domain IPR021780 Nuclear/hormone receptor activator site AF-1
Family IPR000003 Retinoid X receptor/HNF4
Family IPR001723 Nuclear hormone receptor
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear/hormone receptor activator site AF-1 Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Retinoid X receptor/HNF4 Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:E9QHW7 232
UniProtKB:F1Q4V9 458
UniProtKB:A2T929 430
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations