Gene

rxraa

ID

ZDB-GENE-070314-2

Name

retinoid X receptor, alpha a

Symbol

rxraa Nomenclature History

Previous Names

NR2B1-B (1)
RXRalpha-B (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have nuclear receptor activity and retinoic acid-responsive element binding activity. Predicted to be involved in several processes, including regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to localize to RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including nervous system; neural crest; optic vesicle; segmental plate; and tail bud. Orthologous to human RXRA (retinoid X receptor alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

17 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

dq017629 (20 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rxraa Human Ortholog

No data available

Associated With rxraa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Domain	IPR021780	Nuclear/hormone receptor activator site AF-1
Family	IPR000003	Retinoid X receptor/HNF4
Family	IPR001723	Nuclear hormone receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily

Domain Details Per Protein

Protein	Length	Nuclear hormone receptor	Nuclear/hormone receptor activator site AF-1	Nuclear hormone receptor, ligand-binding domain	Nuclear hormone receptor-like domain superfamily	Retinoid X receptor/HNF4	Zinc finger, NHR/GATA-type	Zinc finger, nuclear hormone receptor-type
UniProtKB:E9QHW7 InterPro	232
UniProtKB:F1Q4V9 InterPro	458
UniProtKB:A2T929 InterPro	430

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	rxraa-201 (1) Ensembl	1380 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rxraa-203 (1) Ensembl	878 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rxraa-003 (1) Ensembl	658 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations