Gene

agrp

ID
ZDB-GENE-040817-1
Name
agouti related neuropeptide
Symbol
agrp Nomenclature History
Previous Names
  • agrp1 (1)
  • si:dkey-193l8.2
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Enables melanocortin receptor binding activity and neuropeptide hormone activity. Acts upstream of or within with a positive effect on feeding behavior. Acts upstream of or within several processes, including neuropeptide signaling pathway; positive regulation of feeding behavior; and regulation of growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain; female organism; and male organism. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human AGRP (agouti related neuropeptide).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
27 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With agrp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
obesity Alliance {Leanness, inherited} 601665
obesity Alliance {Obesity, late-onset} 601665
1 - 2 of 2
Associated With agrp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR027300 Agouti domain
Family IPR007733 Agouti
Homologous_superfamily IPR036836 Agouti domain superfamily
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Agouti Agouti domain Agouti domain superfamily
UniProtKB:A0A8M1P467 InterPro 127
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA agrp-201 (1)
Ensembl
Ensembl 555 nt
ZFIN BLAST
mRNA agrp-202 (1)
Ensembl
Ensembl 677 nt
ZFIN BLAST
mRNA agrp-203 (1)
Ensembl
Ensembl 203 nt
ZFIN BLAST
mRNA agrp-204 (1)
Ensembl
Ensembl 1,676 nt
ZFIN BLAST
1 - 4 of 4
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-agrp polyclonal Rabbit
  • IHC
 1
1 - 1 of 1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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