Gene

calca

ID
ZDB-GENE-040718-173
Name
calcitonin/calcitonin-related polypeptide, alpha
Symbol
calca Nomenclature History
Previous Names
  • calc
  • calcitonin
  • cgrp (1)
  • zgc:92886
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable calcitonin receptor binding activity. Acts upstream of or within calcium ion homeostasis and chloride ion homeostasis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including gut; heart; integument; nervous system; and ultimobranchial body. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to several human genes including CALCA (calcitonin related polypeptide alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Wang et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With calca Human Ortholog
No data available
Associated With calca Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018360 Calcitonin, conserved site
Domain IPR001693 Calcitonin peptide-like
Family IPR015476 Calcitonin gene-related peptide
Family IPR021116 Calcitonin/adrenomedullin
Family IPR021117 Calcitonin-like
Family IPR021118 Calcitonin
Domain Details Per Protein
Protein Length Calcitonin Calcitonin/adrenomedullin Calcitonin, conserved site Calcitonin gene-related peptide Calcitonin-like Calcitonin peptide-like
UniProtKB:Q208D2 116
UniProtKB:Q208D3 125
UniProtKB:F1QIK6 133
UniProtKB:G9JKB5 119
UniProtKB:Q6DGJ9 126
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-calca Rabbit
  • IHC
Bachem
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations