ZFIN is now using GRCz12tu for Genomic Data
Gene
nr4a1
- ID
- ZDB-GENE-040704-11
- Name
- nuclear receptor subfamily 4, group A, member 1
- Symbol
- nr4a1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear glucocorticoid receptor binding activity. Predicted to be involved in cellular response to corticotropin-releasing hormone stimulus and regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in axis; myotome; nervous system; and pectoral fin. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- bc074092 (9 images)
- IMAGE:7162027 (1 image)
- MGC:92434 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Xu et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003070 | Nuclear receptor subfamily 4 group A member 1-3 |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Nuclear receptor subfamily 4 group A member 1-3 | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6GMG3 | InterPro | 574 | ||||||
| UniProtKB:A0AC58IJD0 | InterPro | 605 | ||||||
| UniProtKB:A0AC58IJF1 | InterPro | 605 |
- Genome Browsers
Interactions and Pathways
Plasmids
No data available
- Genome Browsers