ZFIN is now using GRCz12tu for Genomic Data

Gene

pitpnaa

ID

ZDB-GENE-040426-744

Name

phosphatidylinositol transfer protein, alpha a

Symbol

pitpnaa Nomenclature History

Previous Names

pitpa (1)
pitpna
zgc:55569 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable several functions, including phosphatidylcholine binding activity; phosphatidylinositol binding activity; and phosphatidylinositol transfer activity. Acts upstream of or within axonogenesis and chordate embryonic development. Located in cytosol and nucleus. Is expressed in several structures, including blood; digestive system; epidermis; nervous system; and periderm. Orthologous to human PITPNA (phosphatidylinositol transfer protein alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55569 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pitpnaa Human Ortholog

No data available

Associated With pitpnaa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR055261	Phosphatidylinositol transfer protein, N-terminal
Family	IPR001666	Phosphatidylinositol transfer protein
Homologous_superfamily	IPR023393	START-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:Q803U3	InterPro	271
UniProtKB:A0AC58HAC3	InterPro	185
UniProtKB:A0AC58HAE0	InterPro	185
UniProtKB:A0AC58HAG3	InterPro	185

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pitpnaa-201 (1) Ensembl	Ensembl	816 nt	Select Tool ZFIN BLAST
mRNA	pitpnaa-202 (1) Ensembl	Ensembl	1,756 nt	Select Tool ZFIN BLAST
mRNA	pitpnaa-203 (1) Ensembl	Ensembl	1,779 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-pitpna	monoclonal	pitpnaa	IgG2a , k	Mouse	WB	Sigma-Aldrich	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations