Gene

nr2f6b

ID

ZDB-GENE-040426-2351

Name

nuclear receptor subfamily 2, group F, member 6b

Symbol

nr2f6b Nomenclature History

Previous Names

nr2f6
EAR2-B (1)
fc72d04
wu:fc72d04
zgc:77260

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure development; cell differentiation; and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including anterior axial hypoblast; axis; gut; mesoderm; and nervous system. Orthologous to human NR2F6 (nuclear receptor subfamily 2 group F member 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

27 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:77260 (24 images)
MGC:77260 (32 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nr2f6b Human Ortholog

No data available

Associated With nr2f6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Family	IPR001723	Nuclear hormone receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily

Domain Details Per Protein

Protein	Length	Nuclear hormone receptor	Nuclear hormone receptor, ligand-binding domain	Nuclear hormone receptor-like domain superfamily	Zinc finger, NHR/GATA-type	Zinc finger, nuclear hormone receptor-type
UniProtKB:A0A8M9Q751 InterPro	409
UniProtKB:Q6P115 InterPro	404

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nr2f6b-201 (1) Ensembl	Havana	2382 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	nr2f6b-202 (1) Ensembl	Havana	467 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	nr2f6b-203 (1) Ensembl	Havana	603 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	nr2f6b-204 (1) Ensembl	Havana	986 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations