Gene
ighm
- ID
- ZDB-GENE-030925-46
- Name
- immunoglobulin heavy constant mu
- Symbol
- ighm Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Acts upstream of or within response to lipopolysaccharide. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; gill; heart; immune system; and integument. Human ortholog(s) of this gene implicated in agammaglobulinemia. Orthologous to human IGHM (immunoglobulin heavy constant mu).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101769 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| agammaglobulinemia | Alliance | Agammaglobulinemia 1 | 601495 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR003599 | Immunoglobulin subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin subtype | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SZQ3
|
499 | |||||||
|
UniProtKB:Q5BJ31
|
570 | |||||||
|
UniProtKB:A8WG82
|
568 |
Interactions and Pathways
No data available
Plasmids