Gene

ighm

ID
ZDB-GENE-030925-46
Name
immunoglobulin heavy constant mu
Symbol
ighm Nomenclature History
Previous Names
  • ighm1
  • IgM (1)
  • mIgM-2 (1)
  • wu:fj14a08
  • zgc:101769
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Acts upstream of or within response to lipopolysaccharide. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; gill; heart; immune system; and integument. Human ortholog(s) of this gene implicated in agammaglobulinemia. Orthologous to human IGHM (immunoglobulin heavy constant mu).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ighm Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
agammaglobulinemia Alliance Agammaglobulinemia 1 601495
Associated With ighm Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Domain IPR003597 Immunoglobulin C1-set
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin C1-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin/major histocompatibility complex, conserved site Immunoglobulin subtype Immunoglobulin V-set domain
UniProtKB:Q7SZQ3 499
UniProtKB:Q5BJ31 570
UniProtKB:A8WG82 568
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ighm polyclonal Rabbit
1
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations