Gene

gjd2b

ID
ZDB-GENE-030911-1
Name
gap junction protein delta 2b
Symbol
gjd2b Nomenclature History
Previous Names
  • gja9 (1)
  • cx35.1 (1)
  • cx35
  • cx35b (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Enables gap junction hemi-channel activity and voltage-gated ion channel activity. Acts upstream of or within cell-cell signaling. Located in gap junction. Part of connexin complex. Is expressed in several structures, including heart; kidney; liver; nervous system; and neural tube. Orthologous to human GJD2 (gap junction protein delta 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Quint et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gjd2b Human Ortholog
No data available
Associated With gjd2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017990 Connexin, conserved site
Domain IPR013092 Connexin, N-terminal
Domain IPR019570 Gap junction protein, cysteine-rich domain
Family IPR000500 Connexin
Homologous_superfamily IPR038359 Connexin, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Connexin Connexin, conserved site Connexin, N-terminal Connexin, N-terminal domain superfamily Gap junction protein, cysteine-rich domain
UniProtKB:Q8JFD6 304
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cx35 monoclonal IgG1 Mouse
  • IHC
  • WB
Millipore
11
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations