ZFIN is now using GRCz12tu for Genomic Data
Gene
bmal1a
- ID
- ZDB-GENE-000509-1
- Name
- basic helix-loop-helix ARNT like 1a
- Symbol
- bmal1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables transcription cis-regulatory region binding activity. Contributes to DNA binding activity. Acts upstream of or within several processes, including photoperiodism; regulation of DNA-templated transcription; and regulation of vasculature development. Part of transcription regulator complex. Human ortholog(s) of this gene implicated in alcohol dependence and bipolar disorder. Orthologous to human BMAL1 (basic helix-loop-helix ARNT like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55263 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Jensen et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000014 | PAS domain |
| Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| Domain | IPR013767 | PAS fold |
| Family | IPR001067 | Nuclear translocator |
| Family | IPR050933 | Circadian Clock Transcription Factors |
| Homologous_superfamily | IPR035965 | PAS domain superfamily |
| Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
| Repeat | IPR001610 | PAC motif |
Domain Details Per Protein
| Protein | Additional Resources | Length | Circadian Clock Transcription Factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Nuclear translocator | PAC motif | PAS domain | PAS domain superfamily | PAS fold |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9I879 | InterPro | 626 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arntl1a-201
(1)
|
Ensembl | 2,343 nt | ||
| mRNA |
arntl1a-202
(1)
|
Ensembl | 2,326 nt | ||
| mRNA |
arntl1a-203
(1)
|
Ensembl | 1,881 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-arntl1a | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers