FIGURE

Fig. 6

ID

ZDB-FIG-251023-44

Publication

Kim et al., 2025 - APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signaling

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Fig. 6

AIBP administration promotes corneal lymphangiogenesis.

a Illustration of murine cornea lymphangiogenesis assay. b Representative images of murine corneal lymphangiogenesis by implantation of pellets containing the indicated recombinant proteins and immunostained using LYVE1 (green) and CD31 (red) antibodies. Enlarged images of the boxed regions are shown in the lower panels. c Quantification of LYVE1⁺ lymphatic vessel area per cornea. VC: VEGFC; AA: AIBP + APOA1; CSD: CAV-1 scaffolding domain peptide. Data are presented as Mean ± SE,and were analyzed using one-way ANOVA with Holm-Sidak’s post-hoc test. n = 8 (control), 9 (VC), 7 (VC + AA), 6 (VC + AIBP), and 9 (VC + CSD) corneas. Scale bar: 1000 μm in upper image and 500 μm in enlarged image. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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