FIGURE

Fig. 2

ID

ZDB-FIG-251022-49

Publication

Fan et al., 2025 - Do variants in the CDH23 gene cause non-syndromic retinitis pigmentosa? Dual validation using whole exome sequencing and a zebrafish model

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Fig. 2

(A) The ocular appearance of wild type and CDH23-knockdown zebrafish at 3 dpf and 6 dpf; (B) H&E-stained retinal sections of wild type and CDH23-knockdown zebrafish at 5 dpf; scale bars: 20 mm; (C) Effects of CDH23 knockdown on retinal thickness in zebrafish. The bar graph presents retinal thickness (μm) for wild type and CDH23-knockdown groups. Data are expressed as mean±SEM (n=5 per group); ns indicates no significant difference between groups (p>0.05, independent-samples t-test) (Representative images shown). GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; IS, inner segment; ONL, outer nuclear layer; OPL, outer plexiform layer; OS, outer segment; RPE, retinal pigment epithelium.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMJ Open Ophthalmol