FIGURE

Fig. 6

ID

ZDB-FIG-250729-93

Publication

Wu et al., 2025 - Mitochondrial dysfunction is driven by imbalanced fission and fusion of mitochondria in myofibrillar myopathy type 5

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Fig. 6

(A-D) Ndufa9 (located in complex I) protein expression was significantly down-regulated in the MO group. Bnip3l protein expression was significantly elevated in the MO group compared with the COMO group. (E) Figure showing the oxygen consumption rate (OCR) curves of the COMO group and the MO group. The difference in the OCR between the COMO group and the MO group before and after the addition of oligo was significant, and the arrow indicates the time of oligo addition (n = 3). (F) The statistical analysis of ATP production capacity (n = 3). (G) Determination of the basic OCR of zebrafish (n = 3). All the data are shown as the means ± SDs. *P < 0.05, **P < 0.01, ***P < 0.001. Statistical significance was calculated via Student’s two-tailed t test.

Expression Data

Antibody:	Ab2-ndufa9
Fish:	WT WT + MO1-flnca + MO2-flncb
Knockdown Reagents:	MO1-flnca MO2-flncb
Anatomical Term:	whole organism
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-flnca + MO2-flncb
Knockdown Reagents:	MO1-flnca MO2-flncb
Observed In:	cellular respiration whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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