FIGURE

Fig. 7

ID

ZDB-FIG-240916-43

Publication

Zhuang et al., 2024 - Slc4a7 Regulates Retina Development in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Slc4a7 mRNA compensation rescues phenotypes in slc4a7-deficient morphants. (A) Enlarged vertical and lateral views of larval eyeballs. Larvae injected with slc4a7 MO and full-length slc4a7 mRNA exhibit normal-sized eyeballs at 3 dpf. Scale bar = 100 mm. (B–D) Statistical analysis of axial length and ocular area. (E,F) VMR testing demonstrates significant recovery of both ON and OFF responses in slc4a7-deficient zebrafish compensated with mRNA compared to those without compensation. n = 20 in each group. Rescue experiments were repeated three times. Bar plots represent the mean ± s.e.m. Data were analyzed using one-way ANOVA followed by Tukey’s post hoc test, *** p < 0.001, **** p < 0.0001, indicate significant differences from the slc4a7 1.00 ng group. ns means no significance. The scattered circles of various colors in the bar chart denote individual values of zebrafish eye-related parameters for different groups.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.