FIGURE

Fig. 1.

ID

ZDB-FIG-240129-244

Publication

Olson et al., 2024 - RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration

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Fig. 1.

Identification of the pLLP transcriptional profile by scRNA-seq. (A) Unsupervised clustering and UMAP reduction diagram of cells derived from Tg(-8.0claudinB: lynGFP)^zf106; TgBAC(cxcr4b:F-tractin-mCherry)^p3 embryos. (B,C) Feature plots of hmx2 and hmx3a identify clusters 0, 7 and 9 as pLLP. (D) Unsupervised reclustering of clusters 0, 7 and 9. (E,F) Feature plots of ki67 and pcna identify cluster 2 as proliferating cells. (G,H) Feature plots of lef1 and notum1a identify cluster 1 as leader cells. (I,J) Feature plots of etv4 and ackr3b identify cluster 0 as follower cells.

Expression Data

Genes:	ackr3b etv4 hmx2 hmx3a lef1 mki67 notum1a pcna (all 8)
Fish:	sk115Tg/sk115Tg; zf106Tg/zf106Tg
Anatomical Terms:	lateral line lateral line primordium lateral line primordium proliferative region
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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