FIGURE
Fig. 6
- ID
- ZDB-FIG-231020-50
- Publication
- Schleser et al., 2023 - Anti-tumoural [NHC(thiolato)]Au(I) complexes derived from HIF-1α inhibitor AC1-004 target the mitochondrial redox system and show antiangiogenic effects in vivo
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Fig. 6
At least 21 zebrafish larvae each were treated with test compounds 9 c, 10 a–c, 17, YC-1 (10 μm), 9 d (5 μm), 9 a, 9 b, 9 e, AC1-004 and auranofin (1 μm) for 48 h. To estimate the antiangiogenic effect, the SIV (subintestinal vessel) area was quantified via ImageJ and quoted as the mean±SD with solvent-treated fish set to 100 %. Significance is given as n.s.: >0.05; *: <0.05; ***: <0.001; ****: <0.0001, One-way ANOVA with Dunnett's multiple comparison test (GraphPad Prism 9). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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