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Fig. 6 At least 21 zebrafish larvae each were treated with test compounds 9 c, 10 a–c, 17, YC-1 (10 μm), 9 d (5 μm), 9 a, 9 b, 9 e, AC1-004 and auranofin (1 μm) for 48 h. To estimate the antiangiogenic effect, the SIV (subintestinal vessel) area was quantified via ImageJ and quoted as the mean±SD with solvent-treated fish set to 100 %. Significance is given as n.s.: >0.05; *: <0.05; ***: <0.001; ****: <0.0001, One-way ANOVA with Dunnett's multiple comparison test (GraphPad Prism 9).
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