FIGURE

Figure 3.

ID
ZDB-FIG-231012-4
Publication
Oyarbide et al., 2023 - SBDSR126T rescues survival of sbds-/- zebrafish in a dose-dependent manner independently of Tp53
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Figure 3.

Phenotype of 10 dpf larvae expressing the human SBDSR126T.

(A) Western blot showed Eif6 without RPL5, and Rpl11 accumulation in the sbds KO fish, but there was no Eif6 accumulation in the SBDSR126T strain. (B) Protein quantification of Western blots as performed with NIH ImageJ. (C) After Sudan black staining, neutrophils were counted and found to be significant lower in the sbds KO background with or without the transgene. (D) qRT-PCR analysis of critical genes involved in ribosomal, metabolic, and tp53-associated pathways.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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