Fig. 8
- ID
- ZDB-FIG-230911-8
- Publication
- Das et al., 2023 - Self-transfecting GMO-PMO chimera targeting Nanog enable gene silencing in vitro and suppresses tumor growth in 4T1 allografts in mouse
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Cause of NGP ASO induced increased chemosensitivity (A) Confocal images after immunofluorescence analysis of MDR1 (shown in red) in control and treated cells after 72 h of combined treatment with antisense and Taxol. Nuclei were stained with DAPI (blue). Quantification of MDR1 intensity per nucleus obtained from confocal immunofluorescence microscopic images (A2) was calculated for 20–25 cells. (B) Western blot analysis reveal MDR1 and ABCG2 downregulation in NGP ASO-treated cells. Data presented as mean ± SEM. ∗p < 0.05. |