FIGURE

Fig. 2

ID

ZDB-FIG-230911-2

Publication

Das et al., 2023 - Self-transfecting GMO-PMO chimera targeting Nanog enable gene silencing in vitro and suppresses tumor growth in 4T1 allografts in mouse

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Fig. 2

Efficacy of NANOG GMO-PMO ASO in downregulating NANOG and related proteins in MCF7

(A and B) (A) Cell viability assay of MCF7cells after treatment with different doses of NGP Scr and (B) with different doses of NGP ASO. (C) Protein expression of NANOG in MCF7 cells treated with 0.5, 1, and 2 μM NGP ASO compared with that in cells treated with 2 μM NANOG ASO IGT-PMO. (D–F) (D) Comparison among NGP Scr, NGP ASO, NP ASO, and Taxol concerning their effect on the expression of NANOG and NANOG-related proteins (E) in MCF7 along with their densitometric analysis (F). Data presented as mean ± SEM. ∗p < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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