FIGURE

Figure 6

ID

ZDB-FIG-230814-244

Publication

De la Cruz et al., 2023 - Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart

Other Figures

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Figure 6

I_Kr and I_Ks inhibitors promote triangulation while I_Ks activators do not square the zebrafish AP shape. (A) Representative traces of the control conditions (black) and in the presence of the I_Kr and I_Ks inhibitors and the combination of inhibitors to show the qualitative effect of the triangulation of the different drug and drugs combination. (B) APD25/APD80 ratio in the control condition and after applying the drug for each drug or combination of drugs. (C) Representative traces in the presence of the PUFA analogues and the combination of E4031/PUFA analogues to show the qualitative effect of triangulation. (D) APD25/APD80 ratio in the control condition and after applying the PUFA analogues or E4031/PUFA analogues for each condition examined. For the drug combination conditions, CONTROL refers to the drug condition previously applied to the combination of drugs (mean ± SEM; * p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.