FIGURE

Figure 2

ID
ZDB-FIG-230131-74
Publication
Bulleeraz et al., 2023 - Leukemia-associated truncation of granulocyte colony-stimulating factor receptor impacts granulopoiesis throughout the life-course
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Figure 2

Effect of G-CSFR truncation mutation on primitive hematopoiesis. Wild-type (wt/wt), heterozygous (wt/mdu26) and homozygous (mdu26/mdu26) mutant csf3r embryos were subjected to WISH at 22 hpf with mpo (A–C), spi1b (E–G) and gata1a (I–K), with representative images shown. Individual embryos were assessed for the number of mpo + (D) or spi1b + (H) cells or the area of gata1a (L) staining, with mean and SEM in red and level of statistical significance indicated (***: p < 0.001, ns: not significant; n=20-30).

Expression Data
Genes:
Fish:
Anatomical Terms:
Stage: 26+ somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: 26+ somites

Phenotype Detail
Acknowledgments
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