Fig. 7
- ID
- ZDB-FIG-221212-7
- Publication
- Lu et al., 2021 - Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
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Figure 7. DC-TEAD3in03 decreases vertebrate appendage growth during the juvenile growth phase. (A) Growth rates of the caudal fins of DMSO-treated and DC-TEAD3in03-treated zebrafish during the juvenile growth phase (starting at 2 months of age). (B) The average and standard deviation of fin lengths of DMSO- and DC-TEAD3in03-treated fish at the indicated time points. (C) Caudal fins of zebrafish before treatments (d0) and after 14 days of continuous treatment (d14). (D) Growth rates of the bodies of DMSO-treated and DC-TEAD3in03-treated zebrafish during the juvenile growth phase (starting at 2 months of age). (E) Measurements of the body length of untreated and treated zebrafish during the juvenile growth phase (starting at 2 months of age). (F) Images displaying zebrafish bodies after treatment with DMSO and DC-TEAD3in03. (G) Growth rates of the caudal fins of DMSO-treated and DC-TEADin1072-treated zebrafish during the juvenile growth phase (starting at 2 months of age). (H) The average and standard deviation of fin lengths of DMSO- and DC-TEADin1072-treated fish at the indicated time points. (I) Caudal fins of zebrafish before treatments (d0) and after 14 days of continuous treatment (d14). (J) Growth rates of the bodies of DMSO-treated and DC-TEADin1072-treated zebrafish during the juvenile growth phase (starting at 2 months of age). (K) Measurements of the body length of untreated and treated zebrafish during the juvenile growth phase (starting at 2 months of age). (L) Images displaying zebrafish bodies after treatment with DMSO and DC-TEADin1072. Scale bars equal 1 mm. |