FIGURE

Fig. 1

ID
ZDB-FIG-221113-1
Publication
Van Dycke et al., 2021 - A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo
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Fig. 1

The antiviral effect of compound 4 against MNV and the HuNoV GI.1 replicon. (A) The antiviral activity of compound 4 against MNV was quantified by (i) virus-induced CPE reduction and (ii) reduction in viral RNA levels. Cellular toxicity was assessed in parallel. n = 3–4 (±SEM). (B) The antiviral activity of compound 4 against the HuNoV GI.1 replicon. Intracellular RNA loads are represented by relative genome quantification of the HuNoV GI.1 replicon versus β-actin. n = 5 (±SEM).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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