FIGURE

FIG 3

ID

ZDB-FIG-220903-10

Publication

Luo et al., 2022 - Bactericidal Synergism between Phage YC#06 and Antibiotics: a Combination Strategy to Target Multidrug-Resistant Acinetobacter baumannii In Vitro and In Vivo

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FIG 3

Time-kill analyses of antibiotic mixtures alone and in combination with bacteriophage YC#06 against B.m#4015 at different MICs at the end of 8 h exposure (A), at the end of 16 h exposure (B), and at the end of 24 h exposure (C). Antibiotic mixtures include chloramphenicol, imipenem, and cefotaxime. “×MIC” shows that the effective antibiotic concentrations used are at n times the MIC. MICs were chosen according to the Clinical and Laboratory Standards Institute guidelines. Synergy was defined as a 2-log₁₀ CFU/mL kill compared to the most effective agent (or double-combination regimen) alone at 24 h. Bactericidal activity was defined as a 3-log₁₀ CFU/mL reduction from baseline. Data are presented as the mean ± standard deviation (SD).

Expression Data

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Antibody Labeling

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Acknowledgments

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