FIGURE

Fig. 4

ID

ZDB-FIG-220816-76

Publication

Tsakoumis et al., 2022 - Impaired leptin signaling causes subfertility in female zebrafish

Other Figures

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Fig. 4

Fig. 4. Relative gene expression of gnrh2 (A), gnrh3 (B) and lepr (C) in the brain and of gnrhr2 (D), gnrhr3 (E), fshb (F), lhb (G) and lepr (H) in the pituitary of lepr+/+ (empty bars) and lepr−/− (filled bars) adult female zebrafish. Data shown as mean ± SE (n = 6). The expression levels of the target genes were normalized to the expression levels of g6pd in the brain samples and to the average of the expression levels of ef1a and rplp0 in the pituitary samples. Significant differences between different groups are indicated by *p < 0.05.

Expression Data

Genes:	fshb gnrh2 gnrh3 gnrhr2 gnrhr3 lepr lhb (all 7)
Fish:	lepr^{sa12953/sa12953}
Anatomical Terms:	brain hypophysis
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	lepr^{sa12953/sa12953}
Observed In:	hypophysis
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 546, Tsakoumis, E., Ahi, E.P., Schmitz, M., Impaired leptin signaling causes subfertility in female zebrafish, 111595, Copyright (2022) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.