FIGURE
Fig. 4
- ID
- ZDB-FIG-220802-24
- Publication
- Joyce et al., 2022 - The regulation of heart rate following genetic deletion of the ß1 adrenergic receptor in larval zebrafish
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 4
The effects of DMSO vehicle (A) and different adrenergic antagonists (B, atenolol, ß1-specific; C, ICI-118551, ß2-specific; D, SR59230A, ß3-specific) and the ß-AR agonist (isoproterenol) on heart rate in 7 dpf adrb1+/+ and adrb1−/− zebrafish larvae. All drugs, except SR59230A (10 μM) were applied at a final concentration of 100 μM. The effects of each antagonist were analyzed in separate three-way ANOVAs. Note that on each panel the four “untreated” bars (i.e., no antagonist) are repeated to provide control data for comparison with a given antagonist; all of the data were collected in the same sessions so the use of the same controls was appropriate. ns, p > 0.05; *p < 0.05; **p < 0.01, ***p < 0.001. N values are shown by individual data points. Bars show means ± SEM.
|
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Acta Physiol. (Oxf).