FIGURE

Fig. 8

ID

ZDB-FIG-220601-33

Publication

Dieterich et al., 2022 - Anomalous diffusion and asymmetric tempering memory in neutrophil chemotaxis

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Fig. 8

Fig 8. Comparison of arriving probabilities by simulations. (A) Probability distributions of first passage times for simulated cells at a distance of 200 μm. Model parameters calculated for the respective experimental conditions were used for simulations as given in Figs 5 and 6. There is a surge of WT neutrophils reaching their target after 20 min, whereas all other cell types show a delayed arrival. (B) Percentage of cells arriving at the target that is located at a distance a from the starting points of the cell ensemble. All simulated wildtype cells arrive at the target within 5 h, whereas CXCR2 inhibition and/or TRPC6 ablation markedly reduce the number of cells arriving at their target.

Expression Data

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Antibody Labeling

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Acknowledgments

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