ZFIN Figure: Zou et al., 2022, Fig. 5

ZFIN ID: ZDB-FIG-220516-45

ZFIN ID: ZDB-FIG-220516-45

Zou et al., 2022 - A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity. Nutrients 14(9) Full text @ Nutrients

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Antibodies:	Ab2-mfn2 Ab4-opa1
Fish:	AB
Condition:	high fat
Anatomical Term:	skeletal muscle
Stage:	Adult

PHENOTYPE:

Fish:	AB
Condition:	high fat
Observed In:	skeletal muscle skeletal muscle mitochondrial crista skeletal muscle mitochondrion
Stage:	Adult

Fig. 5

Figure 5. Long-term HFD feeding induced abnormal mitochondrial fusion and fission. (A,B) Protein expression of OPA1, MFN2, and DRP1. (C) Representative photomicrographs of muscle sections imaged using transmission electron microscopy. M, mitochondria. *, p < 0.05, **, p < 0.01. Data represent means, and error bars represent standard errors of the means. Scale bar in transmission electron microscopy images, 0.5 μm. ND, normal diet; HFD, high-fat diet.

Gene Expression Details No data available

Antibody Labeling Details

Antibody	Assay	Fish	Conditions	Stage	Anatomy
Ab2-mfn2	WB	AB	high fat	Adult	skeletal muscle
Ab4-opa1	WB	AB	high fat	Adult	skeletal muscle

Phenotype Details

Fish	Conditions	Stage	Phenotype
AB	high fat	Adult	skeletal muscle Ab2-mfn2 labeling decreased amount, abnormal
		Adult	skeletal muscle Ab4-opa1 labeling decreased amount, abnormal
		Adult	skeletal muscle mitochondrial crista broken, abnormal
		Adult	skeletal muscle mitochondrion degenerate, abnormal
		Adult	skeletal muscle mitochondrion swollen, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nutrients