Fig. 1
- ID
- ZDB-FIG-220506-2
- Publication
- Venezia et al., 2021 - Modulation of PPAR signaling disrupts pancreas development in the zebrafish, Danio rerio
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Exposure paradigms utilized in this study to assess gene expression, morphology, and adiposity. Embryos were exposed for 24 h from 3 to 4 dpf prior to assessment of gene expression in 4 dpf embryos. PPAR gene expression in embryos greatly increases beginning at 3 dpf, and therefore the gene expression paradigm was fitted to this window of exposure. For morphological experiments, embryos were exposed from 1 to 4 dpf prior to microscopy. To assess adiposity, embryos were exposed from 1 to 5 dpf, and then transferred to clean water until larval imaging at 8 dpf. |