FIGURE

Figure 4

ID

ZDB-FIG-220430-33

Publication

Li et al., 2022 - Profilin 2 and Endothelial Exosomal Profilin 2 Promote Angiogenesis and Myocardial Infarction Repair in Mice

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Figure 4

Exosomal PFN2 enhances the proliferation ability of ECs and OE-exo treated zebrafish showed significantly increased vessel number than exo and control. (A) The exosomes secreted from ECs were identified by electron microscopy. (B) PFN2 expression in exosomes (n = 3, the expression levels were normalized to control). (C) Exosomes could be internalized by ECs. (D) PFN2 and PCNA expression levels in CTL, exosomes from normal ECs (exo), PFN2-overexpressing ECs (OE-exo), and PFN2 knockdown ECs (KD-exo), n = 3, and the expression levels were normalized to control. (E) OE-exo-treated zebrafish showed significantly increased vessel number than exo and control. Exo, exosomes from normal ECs; OE-exo, exosomes from PFN2-overexpressing ECs; CTL, PBS as control. *p < 0.05, one-way ANOVA (Tukey).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cardiovasc Med