FIGURE

Fig. 1B

ID

ZDB-FIG-220218-2

Publication

Wu et al., 2021 - Inhibition of endoplasmic reticulum stress-related autophagy attenuates MCLR-induced apoptosis in zebrafish testis and mouse TM4 cells

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Fig. 1B

Eﬀects of MCLR induced pathohistological damage in zebrafish testes. (A) Histopathological changes in the testes of male zebrafish after exposed to MCLR for 30 days. M: mature sperm, Sc: spermatocyte, Sg: spermatogonia; widen interstitial space (arrow), cellular vacuolation (*). The scale bars: 20 µm.（B）The ultrastructure of zebrafish testis were observed by transmission electron microscope. Swollen mitochondria (*); Vacuoles (△); autophagic vacuoles (★); nuclear heterogeneity (▲); hyperplasia of endoplasmic reticulum associated with mild expansion (arrow); Compared with the control group, the intercellular space was increased significantly (○) and the sperm morphology is obviously abnormal (#).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment by environment: microcystin-LR
Observed In:	testis testis autophagosome testis lysosome
Stage:	Adult

Phenotype Detail

Acknowledgments

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