FIGURE

FIGURE 3

ID

ZDB-FIG-211025-70

Publication

Chen et al., 2021 - NS398 as a potential drug for autosomal-dominant polycystic kidney disease: Analysis using bioinformatics, and zebrafish and mouse models

Other Figures

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FIGURE 3

NS398 down‐regulates the abundance of cell cycle and proliferation‐related signalling proteins. (A) and (B) Western blot showing the effects of NS398 on the levels of cyclin D1 and p21 in Pkd1^−/− (50 μM) and 786‐0 cells (100 μM), respectively. (C) and (D)Western blot showing the effects of NS398 on the levels of phospho‐ and total Akt and ERK in Pkd1^−/− (50 μM) and 786‐0 (100 μM) cells for 24 and 48 h, respectively. GAPDH was used as the loading control (*p < 0.05, t test)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell. Mol. Med.