ZFIN Figure: Leung et al., 2019, Fig. 4

ZFIN ID: ZDB-FIG-210902-330

ZFIN ID: ZDB-FIG-210902-330

Leung et al., 2019 - Neural signatures of sleep in zebrafish. Nature 571:198-204 Full text @ Nature

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	igfn1.1^{nkgsaizGFFD109AGt}; zf3169Tg; zf3262Tg; zf415Tg mchr1b^{sa1871/sa1871}; mchr1a^{zf3170/zf3170}; igfn1.1^{nkgsaizGFFD109AGt}; zf3262Tg; zf415Tg
Conditions:	chemical treatment by environment: carbachol chemical treatment by environment: metronidazole chemical treatment by environment: metronidazole
Observed In:	ependymal cell calcium ion import into cytosol sleep whole organism
Stage:	Days 7-13

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
igfn1.1^{nkgsaizGFFD109AGt}; zf3169Tg; zf3262Tg; zf415Tg	chemical treatment by environment: metronidazole, chemical treatment by environment: carbachol	Days 7-13	ependymal cell calcium ion import into cytosol delayed, abnormal
igfn1.1^{nkgsaizGFFD109AGt}; zf3169Tg; zf3262Tg; zf415Tg	chemical treatment by environment: metronidazole	Days 7-13	sleep decreased occurrence, abnormal
		Days 7-13	whole organism increased behavioural activity, abnormal
mchr1b^{sa1871/sa1871}; mchr1a^{zf3170/zf3170}; igfn1.1^{nkgsaizGFFD109AGt}; zf3262Tg; zf415Tg	standard conditions	Days 7-13	sleep decreased occurrence, abnormal
		Days 7-13	whole organism increased behavioural activity, abnormal
mchr1b^{sa1871/sa1871}; mchr1a^{zf3170/zf3170}; igfn1.1^{nkgsaizGFFD109AGt}; zf3262Tg; zf415Tg	chemical treatment by environment: carbachol	Days 7-13	ependymal cell calcium ion import into cytosol delayed, abnormal

Full text @ Nature