FIGURE

Figure 1

ID

ZDB-FIG-210707-46

Publication

Nishimura et al., 2021 - Toxicity of Jegosaponins A and B from Styrax japonica Siebold et al. Zuccarini in Prostate Cancer Cells and Zebrafish Embryos Resulting from Increased Membrane Permeability

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Figure 1

Jegosaponin A and B from unripe fruits of Styrax japonica Siebold et al. Zuccarini (SJSZ) suppress prostate cancer PC-3 cells. (a) BuOH extract of SJSZ suppresses PC-3 cell viability. n = 8, error bars indicate SD. **** p < 0.0001 compared to control (0.1% DMSO). (b) Fraction 1, 5 and 6 of BuOH extract of SJSZ suppresses cell viability in a dose-dependent manner. n = 8, error bars indicate SD. **** p < 0.0001 compared to control (0.1% DMSO). (c) Chemical structures of jegosaponin A and B. (d) Jegosaponin A and B suppress PC-3 cell viability after 48 h treatment. n = 8, error bars indicate SD. **** p < 0.0001 compared to control (0 μM jegosaponin A). #### p < 0.0001 vs. control (0 μM jegosaponin B).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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