FIGURE

Fig. 3

ID

ZDB-FIG-210603-8

Publication

Kim et al., 2020 - Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

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Fig. 3

There is an increase in LOH in vll–/– embryos in response to X-ray treatments and CRISPR injection. (A) There was an increased LOH in the vhl locus in vll–/– embryos in response to X-ray treatments. ****p < 0.0001, unpaired t-test. (B) Injection of gRNA/Cas9 against vhl locus induced increased LOH at the vhl locus in vll–/– embryos in comparison to vll+/+ wild type embryos. B is a composite image of 14 individual tail images, white lines separate different genotypes. ***p < 0.001, one way ANOVA; Holm-Sidak’s multiple comparison test. Scale bars: 0.5 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vhl^hu2117/+; vhll^i216/i216; sh144Tg
Condition:	x-ray
Observed In:	DNA repair
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Oncotarget