Fig. 3
- ID
- ZDB-FIG-210602-27
- Publication
- Ali et al., 2020 - Comparative genomic analysis of human GLI2 locus using slowly evolving fish revealed the ancestral gnathostome set of early developmental enhancers
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Subset of GLI2-associated CNEs depict seemingly redundant enhancer activity in the pectoral fin-bud of zebrafish. Representative images of live zebrafish transgenic embryos are shown (merged bright-field and fluorescent microscopy), orientation of the embryos is anterior to left, dorsal to top with lateral views. White arrowheads point to the GFP signals in transgenic zebrafish expressing cells in the developing pectoral fin at 48 hpf, A-C, induced by CNE6, CNE7, and CNE8, respectively. CNE6 is GLI2 intragenic element while CNE7 and CNE8 are intergenic elements. hpf, hours postfertilization; pf, pectoral fin; y, yolk sac |