FIGURE

Fig. 9

ID
ZDB-FIG-210504-9
Publication
Kenyon et al., 2021 - Identification of a novel series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity
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Fig. 9

UoS-7692 reduces GTTR loading in cochlear hair cells. Representative micrographs of GTTR fluorescence in cochlear cultures incubated with DMSO (A) and UoS-7692 (B) prior to the addition of GTTR. Scale bar: 25 μm. (C) Comparison of GTTR fluorescence levels in AU by 2-tailed unpaired t test shows a reduction in GTTR loading in cultures treated with UoS-7692 (***P < 0.001). Symbols represent individual OHC fluorescence levels (10 cells from 3 control and 4 UoS-7692–treated cultures: different colors indicate the 3 independent experimental repeats). Error bars show SDM.

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