FIGURE

FIGURE 1

ID

ZDB-FIG-210402-1

Publication

Montgomery et al., 2021 - Repetitive optogenetic stimulation of glutamatergic neurons: An alternative to NMDA treatment for generating locomotor activity in spinalized zebrafish larvae

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FIGURE 1

Locomotor properties of intact spontaneous, NMDA‐induced, and ChR2‐induced fictive swimming. (a–c) Fictive swimming activity was recorded from peripheral motor nerves of intact spontaneously swimming (Intact), spinalized NMDA‐induced (NMDA), and spinalized ChR2‐induced (ChR2) Tg(vglut2a:Gal4ff)^nns20;Tg(UAS:ChR2(H134R)‐mCherry)^umn201 larval preparations (blue lines represent continuous 10 s blue light stimuli). Peripheral motor nerve voltage traces of 10 min (a), 30 s (b), and 3 s (c) are shown. Boxes indicate regions expanded in subsequent panels. (d–f) Mean values of fictive Episode Duration (d), Burst Duration (e), and Burst Frequency (f). Error bars represent SD. Asterisks indicate statistically significant differences between groups.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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