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Figure 5

ID

ZDB-FIG-210319-82

Publication

Somasagara et al., 2021 - Targeted therapy of human leukemia xenografts in immunodeficient zebrafish

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Figure 5

MV4-11 cells in zebrafish xenografts and drug treatment. Proliferation of MV4-11 cells in the zebrafish xenograft model with Ara-C and Aza treatments started from 2 dpf. The zebrafish xenograft embryos were dissociated (control group at 2 dpf and 5 dpf and treatment group at 5 dpf), and labeled leukemia cells were analyzed by ImageXpress Pico. (A) Total MV4-11 cells in zebrafish xenografts after Ara-C (500 µM), Aza (300 µM), and U0126 (10 µM) treatment. (B) Representative images of zebrafish xenografts with respective concentrations of drug treatment at 5 dpf. Quantitative values were means ± SEM from 5 to 8 independent groups of 3 xenografts in each group. Significance p values were determined as *p ≤ 0.05, **p ≤ 0.01 and ***p ≤ 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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