Figure 1—figure supplement 3.

ITGA2 expression correlates with collagen expression in TCGA and GTEx dataset.

(A) Unsupervised hierarchical cluster analysis and heat map visualization of genes encoding collagen-binding integrins (α1, α2, α10, and α11) from gynecologic tissues data obtaining from GTEx database. (B) ITGA2 expression (log(TPM)) in 22 non-diseased tissues from (GTEx dataset). (C) Spearman’s correlation matrix of ITGA2 and selected collagens in the TCGA-ovarian cancer RNA-seq dataset. The top of the diagonal represents pairwise Spearman’s correlation coefficients and significance level (*p<0.05, **p<0.01, ***p<0.001). On the bottom of the diagonal: bivariate scatter plots with a fitted line are displayed. (D) Correlation between a set of top 25 expressed collagen genes (GSVA) and ITGA2 in TCGA and in (E) GTEx RNA-seq dataset.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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