ZFIN Figure: Rödel et al., 2019, Fig. 2

ZFIN ID: ZDB-FIG-200622-32

ZFIN ID: ZDB-FIG-200622-32

Rödel et al., 2019 - Blood Flow Suppresses Vascular Anomalies in a Zebrafish Model of Cerebral Cavernous Malformations. Circulation research 125(10):e43-e54 Full text @ Circ. Res.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Gene:	Citrine
Fish:	mu107Tg mu107Tg + MO1-tnnt2a krit1^{ty219c/ty219c}; md40Tg/+; mu107Tg; ubs3Tg/+ krit1^{ty219c/ty219c}; mu107Tg
Knockdown Reagent:	MO1-tnnt2a
Anatomical Term:	lateral dorsal aorta
Stage:	Long-pec

PHENOTYPE:

Fish:	mu107Tg + MO1-tnnt2a krit1^{ty219c/ty219c}; md40Tg/+; mu107Tg; ubs3Tg/+ krit1^{ty219c/ty219c}; mu107Tg
Knockdown Reagent:	MO1-tnnt2a
Observed In:	blood circulation lateral dorsal aorta
Stage:	Long-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Qualifier	Anatomy	Assay
Citrine	krit1^{ty219c/ty219c}; md40Tg/+; mu107Tg; ubs3Tg/+	control	Long-pec		lateral dorsal aorta	IFL
	krit1^{ty219c/ty219c}; mu107Tg	control	Long-pec		lateral dorsal aorta	IFL
	mu107Tg	control	Long-pec		lateral dorsal aorta	IFL
	mu107Tg + MO1-tnnt2a	control	Long-pec	Not Detected	lateral dorsal aorta	IFL

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
krit1^{ty219c/ty219c}; md40Tg/+; mu107Tg; ubs3Tg/+	control	Long-pec	blood circulation occurrence, ameliorated
		Long-pec	lateral dorsal aorta Citrine expression increased amount, abnormal
krit1^{ty219c/ty219c}; mu107Tg	control	Long-pec	blood circulation decreased occurrence, abnormal
		Long-pec	lateral dorsal aorta Citrine expression increased amount, abnormal
mu107Tg + MO1-tnnt2a	control	Long-pec	blood circulation decreased occurrence, abnormal
		Long-pec	lateral dorsal aorta Citrine expression absent, abnormal

Full text @ Circ. Res.