ZFIN Figure: Tyrkalska et al., 2019, Fig. 2

ZFIN ID: ZDB-FIG-200604-23

ZFIN ID: ZDB-FIG-200604-23

Tyrkalska et al., 2019 - Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. Immunity 51(1):50-63.e5 Full text @ Immunity

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	c264Tg; utn6Tg sh267Tg; ums3Tg sh267Tg; ums5Tg ums3Tg; utn6Tg ums5Tg; utn6Tg c264Tg; utn6Tg + MO4-pycard
Condition:	chemical treatment by environment: EC 3.4.22.36 (caspase-1) inhibitor
Knockdown Reagent:	MO4-pycard
Observed In:	cysteine-type endopeptidase activity involved in apoptotic process hematopoietic multipotent progenitor cell neutrophil
Stage Range:	Long-pec to Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
c264Tg; utn6Tg	chemical treatment by environment: EC 3.4.22.36 (caspase-1) inhibitor	Long-pec	cysteine-type endopeptidase activity involved in apoptotic process decreased occurrence, abnormal
		Long-pec	hematopoietic multipotent progenitor cell amount, normal
		Protruding-mouth	cysteine-type endopeptidase activity involved in apoptotic process decreased occurrence, abnormal
		Protruding-mouth	hematopoietic multipotent progenitor cell amount, normal
c264Tg; utn6Tg + MO4-pycard	control	Protruding-mouth	cysteine-type endopeptidase activity involved in apoptotic process decreased occurrence, abnormal
		Protruding-mouth	hematopoietic multipotent progenitor cell amount, normal
sh267Tg; ums3Tg	control	Protruding-mouth	neutrophil amount, normal
sh267Tg; ums5Tg	control	Protruding-mouth	neutrophil amount, normal
ums3Tg; utn6Tg	control	Protruding-mouth	neutrophil decreased amount, abnormal
ums5Tg; utn6Tg	control	Protruding-mouth	neutrophil decreased amount, abnormal

Full text @ Immunity