FIGURE

FIGURE 1

ID

ZDB-FIG-200423-54

Publication

Zhu et al., 2020 - Functional Characterization and Expression Analyses Show Differential Roles of Maternal and Zygotic Dgcr8 in Early Embryonic Development

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 1

Germline specific dgcr8 deletion has no functional influence on gonad development. (A) A basic schematic diagram of generating dgcr8 germline conditional knockout zebrafish. (B) Real-time analysis of the expression of dgcr8 mRNA and primary miRNAs in ovary of dgcr8 kop-cKO fish. (C) Real-time PCR analysis of the expression of mature miRNAs in ovary of dgcr8 kop-cKO fish. (D) Expression of germline markers in the ovary of dgcr8 kop-cKO. (E) Histology of ovaries in the wild-type and dgcr8 kop-cKO female zebrafish. *p < 0.05, **p < 0.01, and ****p < 0.0001.

Expression Data

Genes:	ddx4 dgcr8 dnmt1 dre-mir-21-1 fshr gdf9 gsdf inha kiss2 lhcgr sox9a
Fish:	WT dgcr8^{zf1064/zf1064}; ihb7Tg/+; zf1065Tg/+
Anatomical Term:	ovary
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dgcr8^{zf1064/zf1064}; ihb7Tg/+; zf1065Tg/+
Observed In:	ovary
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet