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ID
ZDB-FIG-200408-1
Publication
Guo et al., 2020 - Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model
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Figure 1

TGFβ1 increased MDA‐MB‐231 cell invasion and affected cancer cell morphology change. A, MDA‐MB‐231 cells were treated with TGFβ1 (0, 2.5, 5, 10, 20 ng/mL) for 48 h, the cell morphology was analyzed by microscopy. The morphology of the cancer cells changed to an elongated spindle shape (original magnification, ×400). B, MDA‐MB‐231 cells were treated with TGFβ1 (0, 1.25, 2.5, 5, 10, 20 ng/mL) for 24 h in transwell, the invasion cells were stained with 0.1% crystal violet. Invasion cell number was significantly increased at 5, 10, 20 ng/mL TGFβ1‐treated cells compared to control (original magnification, ×100). **P < .01

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